News & Updates

Combining cryoEM data with ligand docking

Improving drug design by using CryoEM data for precise docking of ligands at protein binding sites! We're excited to introduce ChemEM, a...

Modeling flexible protein structures with Alphafold2 and cross-linking MS

Recently, a big leap forward in predicting protein structures came with the development of AlphaFold2, and similar deep learning methods....

Introducing Tempy-ReFF

Check out our latest paper introducing Tempy-ReFF in Nature Communications - authors: Joseph G. Beton, Thomas Mulvaney, Tristan...

Pore-forming protein targeting western corn rootworm

Latest publication in Nature Communications: Pore-forming proteins are soluble proteins able to oligomerize into rings and undergo huge...

RIBFIND2 - published in Nucleic Acids Research

Abstract Molecular structures are often fitted into cryo-EM maps by flexible fitting. When this requires large conformational changes,...

Open PhD Position in LCI project

An exciting opportunity! Apply for a PhD position in a joint project between LIV/CSSB & BNITM! The call is open until 25th of November ...

CECAM workshop 2023 - Lausanne, Switzerland

'Macromolecular complexes: from ab initio and integrative modelling to functional dynamics' September 5, 2023 - September 8, 2023...

Taming New Pathogens - Panel Discussion

Panel Discussion on virus research with AI - with Prof. Dr. Maya Topf, Prof. Dr. Blanche Schwappach-Pignataro & Prof. Dr. Kay Grünewald...

An interview with CASP14 organiser Maya Topf

CSSB and HPI’s newest group leader, Maya Topf (HPI/UKE), was one of the five organizers of the 14th Community Wide Experiment on the...

New Score Assesses Protein-Protein Interfaces

The Topf group (HPI, UKE), at the Centre for Structural Systems Biology CSSB, has created a score to assess protein-protein interactions...