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TEMPy-ReFF is a gaussian mixture modelling method for multiple cryoEM modelling tasks, including refinement, ensemble representation, and composite map generation.

You can download the software here

Beton JG, Mulvaney T, Cragnolini T, Topf M. Cryo-EM structure and B-factor refinement with ensemble representation. Nat. Commun. 2024;15(1):444. DOI:10.1038/s41467-023-44593-1

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