Our Tools

3D-EM Map & Model Analysis

TEMPy-ReFF| Refinement of macromolecular assemblies using 3D-EM maps.

Flex-EM| A method for refinement of protein structures guided by cryoEM density. (Flex-EM tutorial)

RIBFIND2 | Finding rigid bodies in protein and nucleic acid structures.

ChemEM| A tool for docking ligands in cryo-EM maps.

TEMPy| A python library for structural analysis of macromolecular assemblies using 3D-EM maps.

Cluster Fits | Scripts for scoring and clustering fits in a density map.

chimera_diffmap.py | A python script that uses Chimera to calculate difference maps. Instructions.

CHOYCE | A web server for constrained homology modelling with cryoEM maps.

Mod-EM | Density class in MODELLER. A method for rigid body cryoEM density fitting. Tutorial on combining comparative modelling and density fitting, and Mod-EM dataset.